King's College London

Single-cell RNA sequencing unifies developmental programs of Esophageal and Gastric Intestinal Metaplasia

Nowicki-Osuch, K., Zhuang, L., Cheung, T. S., Black, E., Masqué-Soler, N., Devonshire, G., Redmond, A., Freeman, A., di Pietro, M., Pilonis, N., Januszewicz, W., O’Donovan, M., Tavaré, S., Shields, J. & Fitzgerald, R., 17 Mar 2023, In: Cancer discovery.

Research output: Contribution to journal › Article › peer-review

Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem Cells

Mian, S. A., Abarrategi, A., Kong, K. L., Rouault-Pierre, K., Wood, H., Oedekoven, C. A., Smith, A. E., Batsivari, A., Ariza-McNaughton, L., Johnson, P., Snoeks, T., Mufti, G. J. & Bonnet, D., 1 Mar 2021, In: Cancer discovery. 2, 2, p. 135-145 11 p.

Research output: Contribution to journal › Article › peer-review

HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers

Li, B. T., Michelini, F., Misale, S., Cocco, E., Baldino, L., Cai, Y., Shifman, S., Tu, H-Y., Myers, M. L., Xu, C., Mattar, M., Khodos, I., Little, M., Qeriqi, B., Weitsman, G., Wilhelm, C. J., Lalani, A. S., Diala, I., Freedman, R. A., Lin, N. U., & 29 othersSolit, D. B., Berger, M. F., Barber, P. R., Ng, T., Offin, M., Isbell, J. M., Jones, D. R., Yu, H. A., Thyparambil, S., Liao, W-L., Bhalkikar, A., Cecchi, F., Hyman, D. M., Lewis, J. S., Buonocore, D. J., Ho, A. L., Makker, V., Reis-Filho, J. S., Razavi, P., Arcila, M. E., Kris, M. G., Poirier, J. T., Shen, R., Tsurutani, J., Ulaner, G. A., de Stanchina, E., Rosen, N., Rudin, C. M. & Scaltriti, M., 1 May 2020, In: Cancer discovery. 10, 5, p. 674-687 14 p.

Research output: Contribution to journal › Article › peer-review

First-in-human phase i study of fisogatinib (BLU-554) validates aberrant FGF19 signaling as a driver event in hepatocellular carcinoma

Kim, R. D., Sarker, D., Meyer, T., Yau, T., Macarulla, T., Park, J. W., Choo, S. P., Hollebecque, A., Sung, M. W., Lim, H. Y., Mazzaferro, V., Trojan, J., Zhu, A. X., Yoon, J. H., Sharma, S., Lin, Z. Z., Chan, S. L., Faivre, S., Feun, L. G., Yen, C. J., & 15 othersDufour, J. F., Palmer, D. H., Llovet, J. M., Manoogian, M., Tugnait, M., Stransky, N., Hagel, M., Kohl, N. E., Lengauer, C., Sherwin, C. A., Schmidt-Kittler, O., Hoeflich, K. P., Shi, H., Wolf, B. B. & Kang, Y. K., 1 Dec 2019, In: Cancer discovery. 9, 12, p. 1696-1707 12 p.

Research output: Contribution to journal › Article › peer-review

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation

Gachet, S., El-Chaar, T., Avran, D., Genesca, E., Catez, F., Quentin, S., Delord, M., Therizols, G., Briot, D., Meunier, G., Hernandez, L., Pla, M., Smits, W. K., Buijs-Gladdines, J. G., Van Loocke, W., Menschaert, G., Andre-Schmutz, I., Taghon, T., Van Vlierberghe, P., Meijerink, J. P., & 8 othersBaruchel, A., Dombret, H., Clappier, E., Diaz, J-J., Gazin, C., de The, H., Sigaux, F. & Soulier, J., Dec 2018, In: Cancer discovery. 8, 12, p. 1614-1631

Research output: Contribution to journal › Article › peer-review

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Bajrami, I., Marlow, R., van de Ven, M., Brough, R., Pemberton, H. N., Frankum, J., Song, F., Rafiq, R., Konde, A., Krastev, D. B., Menon, M., Campbell, J., Gulati, A., Kumar, R., Pettitt, S. J., Gurden, M. D., Cardenosa, M. L., Chong, I., Gazinska, P., Wallberg, F., & 11 othersSawyer, E. J., Martin, L-A., Dowsett, M., Linardopoulos, S., Natrajan, R., Ryan, C. J., Derksen, P. W. B., Jonkers, J., Tutt, A. N. J., Ashworth, A. & Lord, C. J., 4 Apr 2018, In: Cancer discovery. 8, 4, p. 498-515

Research output: Contribution to journal › Article › peer-review

Germline Mutations in the CDKN2B Tumor Suppressor Gene Predispose to Renal Cell Carcinoma

Jafri, M., Wake, N. C., Ascher, D. B., Pires, D. E. V., Gentle, D., Morris, M. R., Rattenberry, E., Simpson, M. A., Trembath, R. C., Weber, A., Woodward, E. R., Donaldson, A., Blundell, T. L., Latif, F. & Maher, E. R., Jul 2015, In: Cancer discovery. 5, 7, p. 723-9 7 p.

Research output: Contribution to journal › Article › peer-review

Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers

Watkins, J., Weekes, D., Shah, V., Gazinska, P., Joshi, S., Sidhu, B., Gillett, C., Pinder, S., Vanoli, F., Jasin, M., Mayrhofer, M., Isaksson, A., Cheang, M. C. U., Mirza, H., Frankum, J., Lord, C. J., Ashworth, A., Vinayak, S., Ford, J. M., Telli, M. L., & 2 othersGrigoriadis, A. & Tutt, A. N. J., 1 May 2015, In: Cancer discovery. 5, 5, p. 488-505 18 p.

Research output: Contribution to journal › Article › peer-review