King's College London

Effects of a Parenting Intervention for Emotional and Behavioral Problems in Young Autistic Children Under Conditions of Enhanced Uncertainty: Two-Year Follow-up of a Pilot Randomized Controlled Trial Cohort (ASTAR) During the United Kingdom COVID-19 Pandemic

Palmer, M., Carter Leno, V., Hallett, V., Mueller, J. M., Breese, L., Pickles, A., Slonims, V., Scott, S., Charman, T. & Simonoff, E., May 2023, In: Journal of the American Academy of Child and Adolescent Psychiatry. 62, 5, p. 558-567 10 p.

Research output: Contribution to journal › Article › peer-review

Could interventions on physical activity mitigate genomic liability for obesity? Applying the health disparity framework in genetically informed studies

Herle, M., Pickles, A., Pain, O., Viner, R. M., Pingault, J-B. & De Stavola, B. L., Apr 2023, In: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 38, 4, p. 403-412 10 p.

Research output: Contribution to journal › Article › peer-review

Mediation of 6 year mid-childhood follow-up outcomes after pre-school social communication therapy for autistic children (PACT): Randomised controlled trial

Carruthers, S., Pickles, A., Charman, T., McConachie, H., Couteur, A. L., Slonims, V., Howlin, P., Collum, R., Salomone, E., Tobin, H., Gammer, I., Maxwell, J., Parr, J., Leadbitter, K. & Green, J., 23 Feb 2023, (Accepted/In press) In: Journal of child psychology and psychiatry.

Research output: Contribution to journal › Article › peer-review

How do autistic people fare in adult life and can we predict it from childhood?

Forbes, G., Kent, R., Charman, T., Baird, G., Pickles, A. & Simonoff, E., Feb 2023, In: Autism research. 16, 2, p. 458-473 16 p.

Research output: Contribution to journal › Article › peer-review

Factors associated with mental health symptoms among UK autistic children and young people and their parents during the COVID-19 pandemic

Palmer, M., Chandler, S., Carter Leno, V., Mgaieth, F., Yorke, I., Hollocks, M., Pickles, A., Slonims, V., Scott, S., Charman, T. & Simonoff, E., 2023, (Accepted/In press) In: Autism.

Research output: Contribution to journal › Article › peer-review

Homotypic and Heterotypic Continuity in Psychiatric Symptoms From Childhood to Adolescence in Autistic Youth

Carter Leno, V., Hollocks, M. J., Chandler, S., White, P., Yorke, I., Charman, T., Pickles, A., Baird, G. & Simonoff, E., Dec 2022, In: Journal of the American Academy of Child and Adolescent Psychiatry. 61, 12, p. 1445-1454 10 p.

Research output: Contribution to journal › Article › peer-review

Infant Excitation/Inhibition Balance Interacts with Executive Attention to Predict Autistic Traits in Childhood

the EDEN, STAARS Teams, Carter Leno, V., Begum-Ali, J., Goodwin, A., Mason, L., Pasco, G., Pickles, A., Garg, S., Green, J., Charman, T., Johnson, M. H., Jones, E. J. H., Vassallo, G., Burkitt-Wright, E., Eelloo, J., Gareth Evans, D., West, S., Hupton, E., Lewis, L., & 31 othersRobinson, L., Dobbie, A., Drimer, R., Bethell, H., Jones, R., Musson, S., Prem, C., Splitt, M., Horridge, K., Baralle, D., Redman, C., Tomkins, H., Bhojwani, A., Connelly, S., Conti, F., Evans, B., Jackson, M., Powell, E., Agyapong, M., Bazelmans, T., Dafner, L., Ersoy, M., Gliga, T., Haartsen, R., Halkola, H., Hendry, A., Holman, R., Kalwarowsky, S., Kolesnik, A., Narvekar, N. & Taylor, C., Dec 2022, In: Molecular Autism. 13, 1, 46.

Research output: Contribution to journal › Article › peer-review

Modulation of EEG theta by naturalistic social content is not altered in infants with family history of autism

the BASIS TEAM, Dec 2022, In: Scientific Reports. 12, 1, 20758.

Research output: Contribution to journal › Article › peer-review

Longitudinal Associations between Early Childhood Irritability and Adolescent Depression Symptoms in Autistic Children are Mediated by Peer Relationships but Not Educational Engagement

Carter Leno, V., Wright, N., Pickles, A., Bedford, R., Zaidman-Zait, A., Kerns, C., Zwaigenbaum, L., Duku, E., Bennett, T., Georgiades, S., Smith, I., Richards, A., Vaillancourt, T., Szatmari, P. & Elsabbagh, M., 4 Nov 2022, (Accepted/In press) In: Development and Psychopathology.

Research output: Contribution to journal › Article › peer-review

Predictors of language regression and its association with subsequent communication development in children with autism

Pathways in ASD Study Team, Nov 2022, In: Journal of Child Psychology and Psychiatry and Allied Disciplines. 63, 11, p. 1243-1251 9 p.

Research output: Contribution to journal › Article › peer-review

Effectiveness and cost-effectiveness of psychiatric mother and baby units: quasi-experimental study

Howard, L., Trevillion, K., Potts, L., Heslin, M., Pickles, A., Byford, S., Carson, L., Dolman, C., Jennings, S., Johnson, S., Jones, I., McDonald, R., Pawlby, S., Powell, C., Seneviratne, G., Shallcross, R., Stanley, N., Wieck, A. & Abel, K. M., 21 Oct 2022, In: British Journal of Psychiatry. 221, 4, p. 628-636 9 p.

Research output: Contribution to journal › Article › peer-review

Exposure to family stressful life events in autistic children: Longitudinal associations with mental health and the moderating role of cognitive flexibility

Carter Leno, V., Wright, N., Pickles, A., Bedford, R., Zaidman-Zait, A., Kerns, C., Mirenda, P., Zwaigenbaum, L., Duku, E., Bennett, T., Georgiades, S., Smith, I., Vaillancourt, T., Szatmari, P. & Elsabbagh, M., Oct 2022, In: Autism. 26, 7, p. 1656-1667 12 p.

Research output: Contribution to journal › Article › peer-review

Pathways to adaptive functioning in autism from early childhood to adolescence

Chandler, S., Carter Leno, V., White, P., Yorke, I., Hollocks, M. J., Baird, G., Pickles, A., Simonoff, E. & Charman, T., Oct 2022, In: Autism research. 15, 10, p. 1883-1893 11 p.

Research output: Contribution to journal › Article › peer-review

Parent- and teacher-reported associations from adolescent bifactor models of psychopathology: an outcome-wide association study of 26 outcomes in mid-life

Hoffmann, M. S., Evans-Lacko, S., Collishaw, S., Knapp, M., Pickles, A., Shearer, C. & Maughan, B., 24 Sep 2022, (E-pub ahead of print) In: Journal of Child Psychology and Psychiatry and Allied Disciplines.

Research output: Contribution to journal › Article › peer-review

Postnatal maternal depressive symptoms and behavioural outcomes in term- and preterm-born toddlers: a longitudinal UK community cohort study

Kleine, I., Vamvakas, G., Lautarescu, A., Falconer, S., Chew, A., Counsell, S., Pickles, A., Edwards, D. & Nosarti, C., 9 Aug 2022, (Accepted/In press) In: BMJ Open.

Research output: Contribution to journal › Article › peer-review

Parental feeding and childhood genetic risk for obesity: exploring hypothetical interventions with causal inference methods

Herle, M., Pickles, A., Micali, N., Abdulkadir, M. & De Stavola, B. L., Jul 2022, In: International Journal of Obesity. 46, 7, p. 1271-1279 9 p.

Research output: Contribution to journal › Article › peer-review

Assessing the feasibility of a web-based outcome measurement system in child and adolescent mental health services - myHealthE a randomised controlled feasibility pilot study

Morris, A. C., Ibrahim, Z., Heslin, M., Moghraby, O. S., Stringaris, A., Grant, I. M., Zalewski, L., Pritchard, M., Stewart, R., Hotopf, M., Pickles, A., Dobson, R. J. B., Simonoff, E. & Downs, J., 9 Jun 2022, (E-pub ahead of print) In: Child and Adolescent Mental Health.

Research output: Contribution to journal › Article › peer-review

Citalopram Did Not Significantly Improve Anxiety in Children with Autism Spectrum Disorder Undergoing Treatment for Core Symptoms: Secondary Analysis of a Trial to Reduce Repetitive Behaviors

Simonoff, E., Mowlem, F., Pearson, O., Anagnostou, E., Donnelly, C., Hollander, E., King, B. H., McCracken, J. T., Scahill, L., Sikich, L. & Pickles, A., 17 May 2022, (E-pub ahead of print) In: Journal of Child and Adolescent Psychopharmacology. 32, 4, p. 233-241 9 p.

Research output: Contribution to journal › Article › peer-review

Combined social communication therapy at home and in education for young autistic children in England (PACT-G): a parallel, single-blind, randomised controlled trial

Green, J., Leadbitter, K., Ellis, C., Taylor, L., Moore, H. L., Carruthers, S., James, K., Taylor, C., Balabanovska, M., Langhorne, S., Aldred, C., Slonims, V., Grahame, V., Parr, J., Humphrey, N., Howlin, P., McConachie, H., Couteur, A. L., Charman, T., Emsley, R., & 1 othersPickles, A., Apr 2022, In: The lancet. Psychiatry. 9, 4, p. 307-320 14 p.

Research output: Contribution to journal › Article › peer-review

A Comparison of Non-verbal Maternal Care of Male and Female Infants in India and the United Kingdom: The Parent-Infant Caregiving Touch Scale in Two Cultures

Hodsoll, J., Pickles, A., Bozicevic, L., Supraja, T. A., Hill, J., Chandra, P. S. & Sharp, H., 23 Mar 2022, In: Frontiers in Psychology. 13, 852618.

Research output: Contribution to journal › Article › peer-review

Effects of a parenting intervention for emotional and behavioral problems in young autistic children under conditions of enhanced uncertainty: Two-year follow-up of a pilot randomized controlled trial cohort (ASTAR) during the UK COVID-19 pandemic

Palmer, M., Carter Leno, V., Hallett, V., Mueller, J., Breese, L., Pickles, A., Slonims, V., Scott, S., Charman, T. & Simonoff, E., 2022, (Accepted/In press) In: Journal of the American Academy of Child and Adolescent Psychiatry.

Research output: Contribution to journal › Article › peer-review

Perinatal mental health services in pregnancy and the year after birth: the ESMI research programme including RCT

Howard, L. M., Abel, K. M., Atmore, K. H., Bick, D., Bye, A., Byford, S., Carson, L. E., Dolman, C., Heslin, M., Hunter, M., Jennings, S., Johnson, S., Jones, I., Taylor, B. L., McDonald, R., Milgrom, J., Morant, N., Nath, S., Pawlby, S., Potts, L., & 9 othersPowell, C., Rose, D., Ryan, E., Seneviratne, G., Shallcross, R., Stanley, N., Trevillion, K., Wieck, A. & Pickles, A., 2022, In: Programme Grants for Applied Research . 10, 5

Research output: Contribution to journal › Article › peer-review

Psychiatric conditions in autistic adolescents: longitudinal stability from childhood and associated risk factors

Hollocks, M. J., Leno, V. C., Chandler, S., White, P., Yorke, I., Charman, T., Pickles, A., Baird, G. & Simonoff, E., 2022, (Accepted/In press) In: European Child and Adolescent Psychiatry.

Research output: Contribution to journal › Article › peer-review

Lancet Commission on the Future of Care and Clinical Research in Autism

Lord, C., Charman, T., Simonoff, E., Pickles, A., Howlin, P. & Authors, ., 7 Dec 2021, In: The Lancet.

Research output: Contribution to journal › Article › peer-review

A psychometric and validity study of callous-unemotional traits in 2.5 year old children

Wright, N., Pickles, A., Sharp, H. & Hill, J., Dec 2021, In: Scientific Reports. 11, 1, 8065.

Research output: Contribution to journal › Article › peer-review

Behavioural and neural markers of tactile sensory processing in infants at elevated likelihood of autism spectrum disorder and/or attention deficit hyperactivity disorder

BASIS/STAARS Team, Dec 2021, In: Journal Of Neurodevelopmental Disorders. 13, 1, 1.

Research output: Contribution to journal › Article › peer-review

Breast may not always be best: moderation of effects of postnatal depression by breastfeeding and infant sex

Braithwaite, E. C., Sharp, H., Pickles, A., Hill, J. & Wright, N., Dec 2021, In: Biology of Sex Differences. 12, 1, 1 p., 59.

Research output: Contribution to journal › Article › peer-review

INTERSTAARS: Attention training for infants with elevated likelihood of developing ADHD: A proof-of-concept randomised controlled trial

and the INTERSTAARS team, Dec 2021, In: Translational psychiatry. 11, 1, 644.

Research output: Contribution to journal › Article › peer-review

Non-verbal IQ and change in restricted and repetitive behavior throughout childhood in autism: a longitudinal study using the Autism Diagnostic Interview-Revised

Pathways Team, Dec 2021, In: Molecular Autism. 12, 1, 57.

Research output: Contribution to journal › Article › peer-review

Two-stage sampling in the estimation of growth parameters and percentile norms: sample weights versus auxiliary variable estimation

Vamvakas, G., Norbury, C. & Pickles, A., Dec 2021, In: BMC Medical Research Methodology. 21, 1, 173.

Research output: Contribution to journal › Article › peer-review

A Novel Group Parenting Intervention for Emotional and Behavioral Difficulties in Young Autistic Children: Autism Spectrum Treatment and Resilience (ASTAR): A Randomized Controlled Trial

Charman, T., Palmer, M., Stringer, D., Hallett, V., Mueller, J., Romeo, R., Tarver, J., Paris Perez, J., Breese, L., Hollett, M., Cawthorne, T., Boadu, J., Salazar, F., O'Leary, M., Beresford, B., Knapp, M., Slonims, V., Pickles, A., Scott, S. & Simonoff, E., Nov 2021, In: Journal of the American Academy of Child and Adolescent Psychiatry. 60, 11, p. 1404-1418 15 p.

Research output: Contribution to journal › Article › peer-review

Can Interventions Mitigate Genomic Liability for Obesity? Using Causal Inference Based Mediation Analyses in Genetically-Sensitive Studies

Herle, M., Pickles, A. & De Stavola, B. L., Nov 2021, In: Behavior Genetics. 51, 6, p. 709-710

Research output: Contribution to journal › Meeting Abstract

Exploring the impact of adolescent cognitive inflexibility on emotional and behavioural problems experienced by autistic adults

Hollocks, M. J., Charman, T., Baird, G., Lord, C., Pickles, A. & Simonoff, E., 28 Sep 2021, (E-pub ahead of print) In: Autism.

Research output: Contribution to journal › Article › peer-review

Investigating longitudinal associations between parent reported sleep in early childhood and teacher reported executive functioning in school-aged children with autism

Pathways Team, 1 Sep 2021, In: Sleep. 44, 9, zsab122.

Research output: Contribution to journal › Article › peer-review

The association of adverse life events and parental mental health with emotional and behavioral outcomes in young adults with autism spectrum disorder

Hollocks, M. J., Meiser-Stedman, R., Kent, R., Lukito, S., Briskman, J., Stringer, D., Lord, C., Pickles, A., Baird, G., Charman, T. & Simonoff, E., Aug 2021, In: Autism research. 14, 8, p. 1724-1735 12 p.

Research output: Contribution to journal › Article › peer-review

Behavioural and physiological response to frustration in autistic youth: associations with irritability

Carter Leno, V., Forth, G., Chandler, S., White, P., Yorke, I., Charman, T., Pickles, A. & Simonoff, E., 27 Jul 2021, In: Journal Of Neurodevelopmental Disorders. 13, 1, 27.

Research output: Contribution to journal › Article › peer-review

Using a pragmatically adapted, low-cost, contingency management intervention to promote heroin abstinence in individuals undergoing treatment for heroin use disorder in UK drug services (PRAISE): a cluster randomised trial

Metrebian, N., Weaver, T., Goldsmith, K., Pilling, S., Hellier, J., Pickles, A., Shearer, J., Byford, S., Mitcheson, L., Bijral, P., Bogdan, N. A., Bowden-Jones, O., Day, E., Dunn, J., Glasper, A., Finch, E., Forshall, S., Akhtar, S., Bajaria, J., Bennett, C., & 15 othersBishop, E., Charles, V., Davey, C., Desai, R., Goodfellow, C., Haque, F., Little, N., McKechnie, H., Mosler, F., Morris, J., Mutz, J., Pauli, R., Poovendran, D., Philips, E. & Strang, J., 1 Jul 2021, In: BMJ Open. 11, 7, p. e046371 15 p., e046371.

Research output: Contribution to journal › Article › peer-review

Association between spectral electroencephalography power and autism risk and diagnosis in early development

the BASIS TEAM, Jul 2021, In: Autism research. 14, 7, p. 1390-1403 14 p.

Research output: Contribution to journal › Article › peer-review

The Association of Adverse Life Events and Parental Mental Health on Emotional and Behavioural Outcomes in Young Adults with Autism Spectrum Disorder: Life Events and Mental Health in Adults with ASD

Hollocks, M., Meiser-Stedman, R., Kent, R., Lukito, S., Briskman, J., Stringer, D., Lord, C., Pickles, A., Baird, G., Charman, T. & Simonoff, E., 3 May 2021, (Accepted/In press) In: Autism research.

Research output: Contribution to journal › Article › peer-review

Annual Research Review: Anterior Modifiers in the Emergence of Neurodevelopmental Disorders (AMEND)—a systems neuroscience approach to common developmental disorders

Johnson, M. H., Charman, T., Pickles, A. & Jones, E. J. H., May 2021, In: Journal of Child Psychology and Psychiatry and Allied Disciplines. 62, 5, p. 610-630 21 p.

Research output: Contribution to journal › Review article › peer-review

Biological responses to COVID-19: Insights from physiological and blood biomarker profiles

Zakeri, R., Pickles, A., Carr, E., Bean, D. M., O'Gallagher, K., Kraljewic, Z., Searle, T., Shek, A., Galloway, J. B., Teo, J. T. H., Shah, A. M., Dobson, R. J. B. & Bendayan, R., May 2021, In: Current Research in Translational Medicine. 69, 2, 103276.

Research output: Contribution to journal › Article › peer-review

12-Month peak alpha frequency is a correlate but not a longitudinal predictor of non-verbal cognitive abilities in infants at low and high risk for autism spectrum disorder

the BASIS TEAM, Apr 2021, In: Developmental Cognitive Neuroscience. 48, 100938.

Research output: Contribution to journal › Article › peer-review

Predicting Uncertain Multi-Dimensional Adulthood Outcomes From Childhood and Adolescent Data in People Referred to Autism Services

Forbes, G., Lord, C., Elias, R. & Pickles, A., 9 Feb 2021, In: Frontiers in Psychology. 12, 594462.

Research output: Contribution to journal › Article › peer-review

Evaluation and improvement of the National Early Warning Score (NEWS2) for COVID-19: a multi-hospital study

Carr, E., Bendayan, R., Bean, D., Stammers, M., Wang, W., Zhang, H., Searle, T., Kraljevic, Z., Shek, A., Phan, H. T. T., Muruet, W., Gupta, R. K., Shinton, A. J., Wyatt, M., Shi, T., Zhang, X., Pickles, A., Stahl, D., Zakeri, R., Noursadeghi, M., & 28 othersO'Gallagher, K., Rogers, M., Folarin, A., Karwath, A., Wickstrom, K. E., Kohn-Luque, A., Slater, L., Cardoso, V. R., Bourdeaux, C., Holten, A. R., Ball, S., McWilliams, C., Roguski, L., Borca, F., Batchelor, J., Amundsen, E. K., Wu, X., Gkoutos, G. V., Sun, J., Pinto, A., Guthrie, B., Breen, C., Douiri, A., Wu, H., Curcin, V., Teo, J. T., Shah, A. M. & Dobson, R. J. B., 21 Jan 2021, In: BMC Medicine. 19, 1, p. 23 23.

Research output: Contribution to journal › Article › peer-review

Infant Effortful Control Mediates Relations Between Nondirective Parenting and Internalising-Related Child Behaviours in an Autism-Enriched Infant Cohort

the BASIS TEAM, 2021, (Accepted/In press) In: Journal of Autism and Developmental Disorders.

Research output: Contribution to journal › Article › peer-review

Investigating the Mechanisms Driving Referent Selection and Retention in Toddlers at Typical and Elevated Likelihood for Autism Spectrum Disorder

Gliga, T., Skolnick, A., Liersch, U., Charman, T., Johnson, M. H., Bedford, R., Baron-Cohen, S., Bolton, P., Blasi, A., Davies, K., Elsabbagh, M., Fernandes, J., Gammer, I., Guiraud, J., Hendry, A., Liew, M., Lloyd-Fox, S., Maris, H., O'Hara, L., Pasco, G., & 4 othersPickles, A., Ribeiro, H., Salomone, E. & Tucker, L., 2021, (Accepted/In press) In: JOURNAL OF CHILD LANGUAGE. p. 1-13 13 p.

Research output: Contribution to journal › Article › peer-review

Pilot Randomised Controlled Trial of a Novel Group Parenting Intervention for Emotional and Behavioural Difficulties in Young Autistic Children: Feasibility and Preliminary Outcomes

Charman, T., Palmer, M., Stringer, D., Hallett, V., Mueller, J., Romeo, R., Tarver, J., Paris Perez, J., Breese, L., Hollett, M., Cawthorne, T., Kankam-Boadu, J. B., Beresford, B., Knapp, M., Slonims, V., Pickles, A., Scott, S. & Simonoff, E., 2021, In: Journal of the American Academy of Child and Adolescent Psychiatry.

Research output: Contribution to journal › Article › peer-review

Relationship between depressive symptoms during early adulthood and the development of physical multimorbidity in the UK: an observational cohort study.

Arias de la Torre, J., Ronaldson, A., Prina, M., Matcham, F., Pinto Pereira, S. M., Hatch, S., Armstrong, D., Pickles, A., Hotopf, M. & Dregan, A., 2021, In: The Lancet Healthy Longevity.

Research output: Contribution to journal › Article › peer-review

Synergy between callous-unemotional traits and aggression in preschool children: Cross-informant and cross-cultural replication in the UK Wirral Child Health and Development Study, and the Colombian la Sabana Parent-Child Study

Obando, D., Hill, J., Sharp, H., Pickles, A., Fisher, L. & Wright, N., 2021, (Accepted/In press) In: Development and psychopathology.

Research output: Contribution to journal › Article › peer-review