King's College London

• The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

  Opie-Martin, S., Iacoangeli, A., Topp, S. D., Abel, O., Mayl, K., Mehta, P. R., Shatunov, A., Fogh, I., Bowles, H., Limbachiya, N., Spargo, T. P., Al-Khleifat, A., Williams, K. L., Jockel-Balsarotti, J., Bali, T., Self, W., Henden, L., Nicholson, G. A., Ticozzi, N., McKenna-Yasek, D., & 29 othersTang, L., Shaw, P. J., Chio, A., Ludolph, A., Weishaupt, J. H., Landers, J. E., Glass, J. D., Mora, J. S., Robberecht, W., Damme, P. V., McLaughlin, R., Hardiman, O., van den Berg, L., Veldink, J. H., Corcia, P., Stevic, Z., Siddique, N., Silani, V., Blair, I. P., Fan, D. S., Esselin, F., de la Cruz, E., Camu, W., Basak, N. A., Siddique, T., Miller, T., Brown, R. H., Al-Chalabi, A. & Shaw, C. E., Dec 2022, In: Nature Communications. 13, 1, 6901.

  Research output: Contribution to journal › Article › peer-review

• Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data

  Al Khleifat, A., Iacoangeli, A., Jones, A., van Vugt, J., Shatunov, A., Moisse, M., Shatunov, A., Zwamborn, R. A. J., van der Spek, R., Cooper-Knock, J., Topp, S., van Rheenen, W., Kenna, B. J., van Eijk, K. R., Kenna, K. P., Byrne, R. P., López Alonso, V., Opie-Martin, S., Vural, A., González, Y., & 25 othersWeber, M., Smith, B., Fogh, I., Silani, V., Morrison, K. E., Dobson, R., van Es, M. A., McLaughlin, R. L., Chio, A., Corcia, P., de Carvalho, M., Gotkine, M., Panades, M. P., Mora, J. S., Shaw, P. J., Landers, J. E., Glass, J. D., Shaw, C., Başak, A. N., Hardiman, O., Robberecht, W., Van Damme, P., van den Berg, L., Veldink, J. & Al-Chalabi, A., 15 Nov 2022, In: Frontiers in cellular neuroscience.

  Research output: Contribution to journal › Article › peer-review

• Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

  SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N., Westra, H. J., Bakker, O. B., Deelen, P., Shireby, G., Hannon, E., Moisse, M., Baird, D., Restuadi, R., Dolzhenko, E., & 34 othersDekker, A. M., Gawor, K., Westeneng, H. J., Tazelaar, G. H. P., van Eijk, K. R., Kooyman, M., Byrne, R. P., Doherty, M., Heverin, M., Al Khleifat, A., Iacoangeli, A., Shatunov, A., Ticozzi, N., Cooper-Knock, J., Smith, B. N., Gromicho, M., Chandran, S., Pal, S., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Sendtner, M., Meyer, T., Başak, N., van der Kooi, A. J., Ratti, A., Fogh, I., Wood, N. W., Topp, S., Curtis, C. J., Breen, G., Shaw, C. E. & Al-Chalabi, A., Dec 2021, In: Nature genetics. 53, 12, p. 1636-1648 13 p.

  Research output: Contribution to journal › Article › peer-review

• Structural variation analysis of 6,500 whole genome sequences in amyotrophic lateral sclerosis

  Al Khleifat, A., Iacoangeli, A., Van Vugt, J. J. F. A., Bowles, H., Zwamborn, R. A. J., Moisse, M., Zwamborn, R. A. J., Cooper-Knock, J., Shatunov, A., Jones, A., van Rheenen, W., Opie-Martin, S., Fogh, I., Topp, S., Smith, B., Dobson, R., Shaw, C., Chiò, A., Panades, M. P., Mora, J. S., & 10 othersShaw, P. J., Landers, J. E., Glass, J. D., Başak, A. N., Hardiman, O., Robberecht, W., Van Damme, P., van den Berg, L. H., Veldink, J. H. & Al-Chalabi, A., 19 Oct 2021, In: NPJ Genomic medicine.

  Research output: Contribution to journal › Article › peer-review

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